Ning Huang Selected Research

HMGN2 Protein (HMGN2)

12/2019	HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization.
1/2019	High-mobility group protein N2 induces autophagy by activating AMPK/ULK1 pathway and thereby boosts UPEC proliferation within bladder epithelial cells.
1/2019	Effect of HMGN2 on proliferation and apoptosis of MCF-7 breast cancer cells.
1/2018	Non-histone nuclear protein HMGN2 differently regulates the urothelium barrier function by altering expression of antimicrobial peptides and tight junction protein genes in UPEC J96-infected bladder epithelial cell monolayer.
5/2017	Antibacterial mechanism of high-mobility group nucleosomal-binding domain 2 on the Gram-negative bacteria Escherichia coli.
1/2017	Nuclear protein HMGN2 attenuates pyocyanin-induced oxidative stress via Nrf2 signaling and inhibits Pseudomonas aeruginosa internalization in A549 cells.
9/2016	Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of α5β1 integrin expression.
9/2011	High-mobility group protein N2 (HMGN2) inhibited the internalization of Klebsiella pneumoniae into cultured bladder epithelial cells.
1/2008	Creation and anti-cancer potency in HeLa cells of a novel chimeric toxin, HMGNCIDIN, composed of HMGN2 a-helical domain and PE38 KDEL domain III.

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Ning Huang Research Topics

Disease

33	Neoplasms (Cancer) 06/2022 - 01/2008
23	Infections 11/2022 - 10/2003
15	Glioma (Gliomas) 01/2022 - 11/2013
10	Hypoxia (Hypoxemia) 11/2021 - 07/2003
9	Hepatocellular Carcinoma (Hepatoma) 06/2022 - 02/2009
9	Ischemia 03/2013 - 03/2004
8	Inflammation (Inflammations) 01/2020 - 10/2006
6	Necrosis 11/2020 - 03/2003
6	Reperfusion Injury 01/2020 - 02/2005
5	Infarction (Infarctions) 03/2013 - 02/2005
4	Obesity 10/2017 - 09/2014
4	Colonic Neoplasms (Colon Cancer) 01/2015 - 01/2011
3	Body Weight (Weight, Body) 03/2022 - 09/2016
3	Vascular Remodeling 11/2021 - 12/2019
3	Atherosclerosis 10/2021 - 06/2005
3	Carcinoma (Carcinomatosis) 04/2021 - 01/2011
3	Neoplasm Metastasis (Metastasis) 02/2021 - 01/2012
3	Wounds and Injuries (Trauma) 01/2021 - 01/2010
3	Bacterial Infections (Bacterial Infection) 12/2020 - 09/2003
3	Multiple Myeloma 01/2020 - 06/2014
3	Breast Neoplasms (Breast Cancer) 01/2019 - 04/2008
3	Liver Cirrhosis (Hepatic Cirrhosis) 08/2018 - 01/2016
3	Crohn Disease (Crohn's Disease) 03/2016 - 05/2008
2	Colitis 09/2022 - 03/2016
2	Glioblastoma (Glioblastoma Multiforme) 03/2022 - 01/2021
2	Pituitary Neoplasms (Pituitary Adenoma) 02/2022 - 08/2020
2	Ovarian Epithelial Carcinoma 02/2022 - 02/2013
2	Atherosclerotic Plaque (Atheroma) 10/2021 - 01/2017
2	Communicable Diseases (Infectious Diseases) 06/2021 - 01/2017
2	Heart Failure 01/2021 - 03/2018
2	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 01/2021 - 01/2021
2	Pancreatitis 11/2020 - 01/2020
2	Edema (Dropsy) 01/2020 - 01/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 01/2017
2	Fibrosis (Cirrhosis) 08/2018 - 11/2015
2	Weight Gain 10/2017 - 10/2015

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 02/2022 - 03/2004
16	Pharmaceutical PreparationsIBA 01/2022 - 12/2005
9	Messenger RNA (mRNA)IBA 08/2020 - 10/2003
9	HMGN2 Protein (HMGN2)IBA 12/2019 - 01/2008
8	Adenosine Triphosphate (ATP)IBA 11/2021 - 02/2005
7	Biomarkers (Surrogate Marker)IBA 05/2022 - 04/2008
7	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2022 - 01/2013
7	MicellesIBA 06/2021 - 01/2012
6	MicroRNAs (MicroRNA)IBA 05/2022 - 05/2015
6	Therapeutic UsesIBA 10/2021 - 01/2018
6	LipidsIBA 01/2021 - 08/2015
5	Biological ProductsIBA 02/2022 - 02/2013
4	beta-DefensinsIBA 07/2006 - 04/2003
3	Temozolomide (Temodar)FDA LinkGeneric 03/2022 - 10/2017
3	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2017
3	LuteolinIBA 06/2021 - 10/2014
3	PolymersIBA 04/2021 - 11/2012
3	Iodine-125IBA 01/2021 - 11/2017
3	Calgranulin BIBA 11/2020 - 11/2013
3	Hemoglobins (Hemoglobin)IBA 03/2019 - 05/2008
3	NGR peptideIBA 01/2019 - 11/2016
3	Peptides (Polypeptides)IBA 01/2019 - 10/2003
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 12/2018 - 10/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2016 - 03/2004
3	Anti-Bacterial Agents (Antibiotics)IBA 06/2016 - 10/2003
3	QuercetinIBA 01/2015 - 01/2012
3	Mitochondrial Permeability Transition PoreIBA 10/2012 - 08/2008
2	Sincalide FDA Link 06/2022 - 01/2019
2	Hormones (Hormone)IBA 02/2022 - 01/2021
2	Sorafenib (BAY 43-9006)FDA Link 01/2022 - 04/2021
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 11/2021 - 01/2020
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 11/2021 - 01/2020
2	Hematoxylin (Haematoxylon)IBA 10/2021 - 10/2021
2	Eosine Yellowish-(YS) (Eosin)IBA 10/2021 - 10/2021
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2021 - 11/2013
2	methoxy poly(ethylene glycol)-poly(lactide)IBA 06/2021 - 11/2013
2	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 02/2021 - 12/2015
2	AntioxidantsIBA 01/2021 - 01/2017
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2021 - 03/2018
2	Arginine (L-Arginine)FDA Link 11/2020 - 01/2020
2	APTIBA 07/2020 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 07/2020 - 06/2012
2	PyocyanineIBA 01/2020 - 01/2017
2	AntigensIBA 01/2020 - 11/2014
2	InterferonsIBA 01/2020 - 09/2018
2	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 01/2017
2	Pregnenolone Carbonitrile (PCN)IBA 01/2020 - 01/2017
2	Nuclear Proteins (Protein, Nuclear)IBA 01/2019 - 01/2017
2	polydopamineIBA 01/2019 - 11/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2018 - 04/2015
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2018 - 10/2012
2	Dinoprostone (PGE2)FDA Link 09/2018 - 11/2013
2	Protein Kinases (Protein Kinase)IBA 09/2018 - 10/2017
2	Small Interfering RNA (siRNA)IBA 01/2018 - 11/2016
2	Alpha-Ketoglutarate-Dependent Dioxygenase FTOIBA 10/2017 - 01/2017

Therapy/Procedure

26	Therapeutics 02/2022 - 11/2004
4	Drug Therapy (Chemotherapy) 03/2022 - 01/2015
4	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2020 - 11/2015
4	Intravenous Injections 01/2019 - 02/2005
3	Brachytherapy 01/2021 - 11/2017
3	Quantum Dots (Quantum Dot) 08/2018 - 01/2017
3	Intravenous Administration 03/2013 - 01/2009
3	Transplantation 03/2013 - 12/2003
2	Microbubbles 01/2021 - 01/2021